Is depression an independent aetiologic and prognostic factor for coronary heart disease?
The independent role of depression as a risk factor for coronary heart disease remains unestablished due to confounding by conventional risk factors and disease severity in existing observational studies.
Depression has yet to be established as an independent risk factor for CHD because of incomplete and biased availability of adjustment for conventional risk factors and severity of coronary disease.
Nicholson et al. (Fri,) studied this question.