September 1, 2018Circulation Cardiovascular Interventions128 citationsOpen Access
View Full PaperEarly Natural History of Spontaneous Coronary Artery Dissection
Structured PICO
What is the early risk of serious deterioration in patients with conservatively managed spontaneous coronary artery dissection?
P
Population
Patients with conservatively managed Spontaneous Coronary Artery Dissection (SCAD)
I
Intervention
Conservative management
O
Outcome
Serious deterioration within 6 days
Conservatively managed SCAD has a high early risk of clinical deterioration (1 in 6 patients within 6 days), particularly in those presenting with isolated intramural hematoma.
Abstract
Conservatively managed SCAD carries a 1:6 hazard for serious deterioration within 6 days. The risk was higher in those with isolated IMH at baseline. IMH often precedes development of intimal dissection, which has implications for mechanisms of SCAD.