Clopidogrel
Clopidogrel absorption and active metabolite formationsurrogate
P-glycoprotein efflux and the MDR1 C3435T genotype diminish clopidogrel absorption and active metabolite formation.
Clopidogrel absorption and thereby active metabolite formation are diminished by P-gp-mediated efflux and are influenced by the MDR1 C3435T genotype.
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Dirk Taubert
University Hospital Cologne
N VONBECKERATH
University of Cologne
Gundula Grimberg
Rutgers, The State University of New Jersey
Clinical Pharmacology & Therapeutics
Technical University of Munich
University of Cologne
Deutsches Herzzentrum der Charité
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Taubert et al. (Wed,) studied this question.
synapsesocial.com/papers/69da216d0d540cafc58386c2 — DOI: https://doi.org/10.1016/j.clpt.2006.07.007
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