Multisite Spinal Cord and Canal Morphometry Reveals Age-Linked and Sex-Linked Structural Vulnerability in Degenerative Cervical Myelopathy Outcomes

Key Points

• The research aims to explore how age and sex influence the structural features of the spinal cord in degenerative cervical myelopathy (DCM).
• Utilized automated spinal cord morphometry across multiple sites.
• Analyzed morphometric data based on age and sex dependencies.
• Identified anatomical differences relevant to DCM outcomes.
• Found significant age-dependent structural variations in the spinal cord related to DCM.
• Revealed sex-specific morphological changes impacting surgical outcomes.
• Established individualized biomarkers for monitoring DCM progression.