The Front Cover shows a copper-catalyzed tandem strategy that enables the efficient synthesis of triazole-fused quinazolinones through a multicomponent reaction of 2-bromophenyl quinazolinones, sodium azide, and terminal alkynes. Integrating CuAAC and Ulmann-type C–N coupling under mild, ligand-free conditions, this method yields diverse polycyclic N-heterocycles with broad substrate scope. More information can be found in the Research Article by M. Alla and co-workers (DOI: 10.1002/ejoc.202501064).
Kandula et al. (Wed,) studied this question.