Does plasma endothelin-1 correlate with the extent of pulmonary hypertension in patients with chronic congestive heart failure?
Plasma endothelin-1 levels correlate with the severity of pulmonary hypertension in patients with chronic congestive heart failure, suggesting a potential role as a biomarker or mediator.
Elevated immunoreactive endothelin-1 specifically correlated with the extent of pulmonary hypertension in congestive heart failure patients. Whether endothelin-1 is a regional mediator of pulmonary hypertension or a marker for its occurrence requires additional evaluation.
Cody et al. (Sat,) studied this question.