What question did this study set out to answer?

To report a case of NUT carcinoma presenting as a rapidly enlarging mass in the lacrimal apparatus.

May 6, 2026International Journal of Surgical Pathology0 citations

NUT Carcinoma of the Lacrimal Apparatus Presenting as a Rapidly Enlarging Medial Canthal Mass: A Case Report

PSPratiksha Vidhe SharmaSymbiosis International University HLHarshala H. LokhandeSymbiosis International University SVShruti VimalSymbiosis International University

Key Points

To report a case of NUT carcinoma presenting as a rapidly enlarging mass in the lacrimal apparatus.
Case report of a young patient with a medial canthal mass
Prompt biopsy with immunohistochemistry was performed
Assessment of tumor markers, including CD99 and NKX2.2
Biopsy confirmed the diagnosis of NUT carcinoma
CD99 and NKX2.2 were negative
Multidisciplinary management highlighted as critical for patient outcomes

Abstract

positivity; CD99 and NKX2.2 were negative-confirming NC.ConclusionLacrimal sac/gland NC should be considered in rapidly enlarging medial canthal masses in young patients. Prompt biopsy with IMMUNOHISTOCHEMISTRY for NUT and early multidisciplinary management are critical.

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