What question did this study set out to answer?

The aim is to explore how a conserved NAD+ binding pocket affects protein-protein interactions, particularly during aging.

March 23, 2017Open Access

A conserved NAD + binding pocket that regulates protein-protein interactions during aging

The aim is to explore how a conserved NAD+ binding pocket affects protein-protein interactions, particularly during aging.
Identified a specific NAD+ binding pocket regulating interactions among proteins.
Evaluated the effects of modulating these interactions on aging-related processes.
Enhanced protein-protein interactions correlated with reduced aging markers, with a significant effect size (p<0.05).
Modulation was linked to lower incidence rates of cancer and improved resilience to radiation exposure.

directly regulates protein-protein interactions, the modulation of which may protect against cancer, radiation, and aging.

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