Vitamin D Deficiency and Risk of Cognitive Decline and Dementia: Implications and Prevention Strategies

Key Points

• This research examines the link between vitamin D deficiency and cognitive decline, especially in dementia like Alzheimer's disease.
• Reviewed epidemiological evidence connecting vitamin D deficiency with cognitive impairment.
• Explored mechanisms of this association and the effectiveness of current supplementation strategies.
• Proposed personalized interventions based on genetic factors and routine vitamin D status testing for older adults.
• Identified significant association between vitamin D deficiency and increased dementia risk.
• Highlighted that current vitamin D supplementation strategies may not be universally effective.
• Emphasized need for personalized approaches to optimize vitamin D's preventive impact.