99mTc-stannous glucoheptonate (TcSnG) successfully identified acute myocardial infarcts in dogs, demonstrating a maximum 20:1 radioactivity ratio of infarcted to normal myocardium at 24 hours.
Effect estimate: 20:1 ratio
99mTc-stannous glucoheptonate (TcSnG) was evaluated in 5 mongrel dogs three to six hours after intravenous administration of the radiopharmaceutical following surgical ligation of the anterior descending coronary artery. Infarcts were easily identified on imaging and demonstrated a maximum 20:1 radioactivity ratio of infarcted to normal myocardium 24 hours after ligation. 99mTcSnG is a suitable agent for the detection and localization of the acute infarct.
Bennettt et al. (Fri,) conducted a other in Acute myocardial infarct (n=5). 99mTc-stannous glucoheptonate (TcSnG) was evaluated on Radioactivity ratio of infarcted to normal myocardium (20:1 ratio). 99mTc-stannous glucoheptonate (TcSnG) successfully identified acute myocardial infarcts in dogs, demonstrating a maximum 20:1 radioactivity ratio of infarcted to normal myocardium at 24 hours.