Twelve weeks of leg resistance training in healthy older men significantly increased plasma nitric oxide concentration from 39.6 to 61.2 µmol/l without increasing central arterial stiffness.
Absolute Event Rate: 61.2% vs 39.6%
p-value: p=<0.05
BACKGROUND: Little information is available on the effect of strength training on vascular function, particularly in older people. OBJECTIVE: To determine the effect of resistance training on arterial stiffness and endothelial function in older adults. METHOD: Eleven healthy men (mean (SEM) age 64 (1) years) performed 12 weeks of resistance training involving knee flexion and extension (three sets a day, two days a week). RESULTS: Resistance training increased maximal muscle power by 16% (p<0.0001). Arterial stiffness as assessed by aortic pulse wave velocity did not change with resistance training. Plasma concentration of nitric oxide (NO), measured as its stable end product (nitrite/nitrate), had increased (p<0.05) after resistance training (61.2 (10.4) v 39.6 (3.2) micromol/l). There was no change in plasma concentration of endothelin-1. CONCLUSION: The results suggest that short term resistance training may increase NO production without stiffening central arteries in healthy older men.
Maeda et al. (Fri,) conducted a other in Healthy older men (n=11). Leg resistance training vs. Baseline (before training) was evaluated on Plasma nitrite/nitrate (NOx) concentration (µmol/l) (p=<0.05). Twelve weeks of leg resistance training in healthy older men significantly increased plasma nitric oxide concentration from 39.6 to 61.2 µmol/l without increasing central arterial stiffness.