Elevated whole blood viscosity significantly predicted high thromboembolic risk as assessed by CHA2DS2-VA (AUC 0.690) and CHA2DS2-VASc scores in patients with non-valvular atrial fibrillation.
Observational (n=150)
No
Is whole blood viscosity associated with CHA2DS2-VASc/CHA2DS2-VA scores in patients with atrial fibrillation?
Whole blood viscosity correlates with CHA2DS2-VASc/CHA2DS2-VA scores and may serve as an additional marker for thromboembolic risk in atrial fibrillation.
Effect estimate: AUC 0.690 (95% CI 0.610-0.763)
p-value: p=<0.001
INTRODUCTION: CHA2DS2-VASc and CHA2DS2-VA scores are often used to demonstrate thromboembolic risk in nonvalvular atrial fibrillation. Elevated whole blood viscosity is an independent risk factor for ischemic stroke. OBJECTIVE: This study aimed to ascertain the correlation between whole blood viscosity and CHA2DS2-VASc/CHA2DS2-VA scores. METHODS: This study was performed retrospectively in a tertiary cardiac facility, encompassing 150 patients. RESULTS: : <0.05). CONCLUSION: Whole blood viscosity had a substantial correlation with the CHA2DS2-VASc/CHA2DS2-VA scores in patients with atrial fibrillation and may be used to evaluate thromboembolism risk, akin to these scores.
Kahraman et al. (Tue,) conducted a observational in Non-valvular atrial fibrillation (n=150). Whole blood viscosity was evaluated on Prediction of high CHA2DS2-VA score using High Shear Rate (HSR) (AUC 0.690, 95% CI 0.610-0.763, p=<0.001). Elevated whole blood viscosity significantly predicted high thromboembolic risk as assessed by CHA2DS2-VA (AUC 0.690) and CHA2DS2-VASc scores in patients with non-valvular atrial fibrillation.
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