Apixaban's main degradation pathways under stress conditions were established using liquid chromatography coupled to multistage high-resolution mass spectrometry.
This study establishes the degradation pathways of apixaban under stress conditions using advanced mass spectrometry techniques.
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The main degradation pathways of apixaban, a novel anticoagulant drug acting as factor Xa inhibitor, has been established based on the degradation products identification using liquid chromatography coupled to multistage high resolution mass spectrometry.
Secrétan et al. (Thu,) reported a other. Apixaban's main degradation pathways under stress conditions were established using liquid chromatography coupled to multistage high-resolution mass spectrometry.