Moderate or high occupational physical activity was associated with a reduced 10-year risk of CHD events in men (HR 0.66 for moderate vs low; Ptrend<0.001) and women.
Cohort (n=41,053)
Does moderate or high physical activity reduce the 10-year risk of coronary heart disease events in adults without a history of CHD or stroke?
Moderate or high levels of physical activity are associated with a reduced 10-year risk of CHD events across all levels of baseline Framingham risk.
Hazard Ratio: 0.66
p-value: p=<0.001
AIMS: To determine joint associations of different kinds of physical activity and the Framingham risk score (FRS) with the 10-year risk of coronary heart disease (CHD) events. METHODS AND RESULTS: Study cohorts included 41 053 Finnish participants aged 25-64 years without history of CHD and stroke. The multivariable-adjusted 10-year hazard ratios (HRs) of coronary events associated with low, moderate, and high occupational physical activity were 1.00, 0.66, and 0.74 (Ptrendor=20%) risk of the FRS. CONCLUSION: Moderate or high levels of occupational or leisure-time physical activity among both men and women, and daily walking or cycling to and from work among women are associated with a reduced 10-year risk of CHD events. These favourable effects of physical activity on CHD risk are observed at all levels of CHD risk based on FRS assessment.
Hu et al. (Mon,) conducted a cohort in Coronary heart disease (n=41,053). Occupational, commuting, and leisure-time physical activity vs. Low physical activity was evaluated on 10-year risk of coronary events (HR 0.66, p=<0.001). Moderate or high occupational physical activity was associated with a reduced 10-year risk of CHD events in men (HR 0.66 for moderate vs low; Ptrend<0.001) and women.
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