Central arterial stiffness (c-fPWV ≥ 7.6 m/s) or medication use was associated with higher central systolic pressure compared to healthy vascular aging (111-112 vs 99 mmHg, P<0.05).
Cross-Sectional (n=102)
Older individuals with optimal peripheral blood pressure may still exhibit central arterial stiffness and lack healthy vascular aging.
p-value: p=< 0.05
INTRODUCTION: Pulse wave velocity is used to diagnose central arterial stiffness (CAS) and quantify healthy vascular aging (HVA). OBJECTIVE: To evaluate the CAS and HVA in elderly patients with systemic blood pressure levels classified as optimal/normal. METHODS: A total of 102 patients without comorbidities and with systolic pressure (SP) < 120 mmHg and diastolic pressure (DP) < 80 mmHg were selected from the EVOPIU database (Pulse Wave Velocity of Elderly Individuals in an Urban area of Brazil). The carotid-femoral pulse wave velocity (c-fPWV) and the central and peripheral pressures were evaluated in all patients. The patients were divided into four groups: G1: (n = 19, with c-fPWV < 7.6 m/s, without medication), G2 (n = 26, c-fPWV ≥ 7.6 m/s; without medication), G3 (n = 25, c-fPWV < 7.6 m/s with antihypertensive medication), and G4 (n = 32, c-fPWV ≥ 7.6 m/s with antihypertensive medication). RESULTS: In our sample, 56.7% of patients had c-fPWV ≥ 7.6 m/s. The central systolic pressure in G1 99 (10) mmHg was lower than that found in the other three groups vs. 112 (14) mmHg, 111 (15), 112 (20) mmHg; P < 0.05). CONCLUSION: Older people with optimal arterial blood pressure do not necessarily have HVA and could have c-fPWV values close to the limits established for CAS diagnosis.
Jiticovski et al. (Fri,) conducted a cross-sectional in Optimal blood pressure (n=102). Central arterial stiffness (c-fPWV ≥ 7.6 m/s) and/or antihypertensive medication use vs. c-fPWV < 7.6 m/s without medication was evaluated on Central systolic pressure (p=< 0.05). Central arterial stiffness (c-fPWV ≥ 7.6 m/s) or medication use was associated with higher central systolic pressure compared to healthy vascular aging (111-112 vs 99 mmHg, P<0.05).
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