Supplementary Figure S6 from Blocking NRF2 Translation by Inhibition of Cap-Dependent Initiation Sensitizes Lymphoma Cells to Ferroptosis and CAR T-cell Immunotherapy

Puntos clave

• Inhibiting nrf2 translation increased lymphoma cell sensitivity to ferroptosis.
• Significant lipid peroxidation and ROS levels were observed post-intervention.
• Bliss synergy plots support the efficacy of combining therapies in lymphoma treatment.
• This approach highlights the potential for improved immunotherapy outcomes in lymphoma patients.