Supplementary Figure 5 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer

Key Points

• MAIN FINDING: ISR pathway inhibition significantly affects immune cell populations in lung cancer.
• KEY EVIDENCE: Data demonstrate changes in multiple immune checkpoints due to ISR pathway blockage.
• APPROACH: The effect was evaluated using in vivo models to assess immune cell populations.
• SIGNIFICANCE: This research highlights potential strategies for enhancing cancer immunotherapy by targeting the ISR pathway.