Supplementary Figure 1 from The XPO1 Inhibitor Eltanexor Modulates the Wnt/β-Catenin Signaling Pathway to Reduce Colorectal Cancer Tumorigenesis

Key Points

• MAIN FINDING: XPO1 expression impacts colorectal cancer outcomes, particularly in microsatellite stable variants.
• KEY EVIDENCE: Overexpression of XPO1 correlates with poorer prognosis in MSS colorectal cancer cases.
• APPROACH: Analysis of XPO1 levels across various stages of colorectal cancer was conducted.
• SIGNIFICANCE: Understanding XPO1's role may guide therapeutic strategies to improve colorectal cancer prognosis.