Impact of margin to depth of invasion ratio on oncologic outcome in locally advanced oral cancer undergoing surgery and chemoradiotherapy.

Key Points

• The study aims to evaluate the impact of the margin to depth of invasion ratio on the oncologic outcomes of locally advanced oral cancer post-treatment.
• Analyzed oncologic outcomes in patients with locally advanced oral cancer
• Utilized surgery and chemoradiotherapy as treatment modalities
• Identified a specific cutoff of 0.35 for the margin to depth of invasion ratio
• MDR was found to be an independent prognostic marker
• A cutoff of 0.35 effectively stratified survival risk
• Incorporating MDR improved postoperative assessment and treatment planning