Analysis reveals that margin to depth of invasion ratio predicts survival in patients with advanced oral cancer, indicating a need for personalized treatment plans.
MDR is an independent prognostic marker in LAOSCC treated with surgery and adjuvant CCRT. A cutoff of 0.35 effectively stratifies survival risk, even among patients with adequate surgical margins. Incorporating MDR into postoperative assessment could refine risk stratification and guide individualized follow-up and adjuvant treatment planning.
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Mh et al. (2026) studied this question.
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