Early in-stent restenosis (E-ISR) exhibited homogeneous neointima in 26.7% of cases compared to 4.4% in late in-stent restenosis (L-ISR), with a P-value of 0.02.
Observational (n=53)
No
Do neointimal tissue characteristics differ between early and late in-stent restenosis after second-generation drug-eluting stent implantation?
Early in-stent restenosis after second-generation DES is primarily driven by neointimal hyperplasia, whereas late restenosis is predominantly caused by neoatherosclerosis.
Absolute Event Rate: 26.7% vs 4.4%
p-value: p=0.02
Neointimal tissue characteristics differed between E-ISR and L-ISR after second-generation DES implantation. E-ISR was mainly caused by neointimal hyperplasia, whereas neoatherosclerosis was the main mechanism of L-ISR.
Jinnouchi et al. (Sun,) conducted a observational in in-stent restenosis after second-generation drug-eluting stents (n=53). Second-generation drug-eluting stents vs. Bare-metal stents was evaluated on Differences in neointimal tissue characteristics between early (E-ISR) and late (L-ISR) in-stent restenosis (p=0.02). Early in-stent restenosis (E-ISR) exhibited homogeneous neointima in 26.7% of cases compared to 4.4% in late in-stent restenosis (L-ISR), with a P-value of 0.02.