Genome-wide reconstruction of the intrinsic apoptosis pathway in Haemonchus contortus

Key Points

• The study aims to reconstruct the intrinsic apoptosis pathway in Haemonchus contortus to elucidate its structural and regulatory features.
• Conducted genome-wide analysis of Haemonchus contortus
• Identified conserved structural features of apoptosis
• Examined developmental regulation of apoptosis
• Defined a comprehensive molecular framework of the intrinsic apoptosis pathway
• Highlighted key apoptotic regulators for further functional studies
• Provided potential targets for developing new anthelmintic treatments