Genetic modulation of omega-3 and omega-6 polyunsaturated fatty acid metabolism and health outcomes: A systematic review

Key Points

• This research aims to understand how genetic variations affect the metabolism of omega-3 and omega-6 fatty acids and their health impacts.
• Conducted a systematic review of existing literature
• Analyzed inter-individual responses to PUFA interventions
• Assessed the role of genetic factors in fatty acid metabolism
• Significant variability in responses to omega-3 and omega-6 interventions was observed
• Genetic differences were identified as key contributors to metabolic variations
• Standardized dietary recommendations may not be applicable for everyone