Description of the Novel HLA‐DQB1*03:03:31 Allele, Identified in a Chinese Individual

Key Points

• To describe the novel HLA-DQB1*03:03:31 allele and its genetic differences from HLA-DQB1*03:03:02:02.
• Identification of novel allele
• Genetic sequencing
• Comparison with existing alleles
• The novel allele differs by one synonymous nucleotide substitution
• The substitution occurs in exon 2
• Illustrates genetic variation within the HLA region