A bioinspired, pH-responsive microsphere matrix of cold-water extracted Colocasia esculenta mucilage and alginate: a new approach for sustained oral delivery of tramadol
Key Points
The new microsphere matrix effectively enhances oral delivery of tramadol with sustained release.
Key evidence shows that this system delays tramadol release significantly when exposed to varying pH levels.
Assessment uses a bioinspired strategy employing natural polymers like mucilage and alginate for drug formulation.
This advancement supports broader applications in drug delivery, specifically utilizing plant-derived materials.
Abstract
Natural polymers derived from plant mucilages are increasingly explored as release-modifying agents in advanced drug delivery systems.
A bioinspired, pH-responsive microsphere matrix of cold-water extracted Colocasia esculenta mucilage and alginate: a new approach for sustained oral delivery of tramadol | Synapse