Higher Incidence of Severe Acute GVHD and NRM Following High Dose Cyclophosphamide Based Conditioning Regimen in Overweight and Obese Patients Undergoing Allogeneic HCT
Key Points
Severe acute GVHD and non-relapse mortality rates are significantly higher in overweight and obese patients.
A notable 30% increase in non-relapse mortality was observed in obese individuals.
Analysis involved assessment of outcomes following a high dose cyclophosphamide conditioning regimen.
These findings indicate the need for tailored conditioning strategies in overweight and obese transplant recipients.
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Higher Incidence of Severe Acute GVHD and NRM Following High Dose Cyclophosphamide Based Conditioning Regimen in Overweight and Obese Patients Undergoing Allogeneic HCT | Synapse