March 3, 2026Open Access

Fourteen Year Outcomes of a Randomised Controlled Trial Comparing Endovenous Laser Ablation, High Ligation and Stripping, and Ultrasound Guided Foam Sclerotherapy for Great Saphenous Varicose Veins

Key Points

UGFS showed inferior outcomes with greater recurrent reflux and re-intervention rates compared to HLS and EVLA.
HLS and EVLA had comparable effectiveness regarding both recurrent reflux and re-intervention rates over 14 years.
The study utilized a randomized controlled trial design to assess the effectiveness of the three treatments.
Quality of life among patients was similar across all treatment groups, indicating consistent patient satisfaction.

Abstract

UGFS demonstrated inferior outcomes in terms of GSV recurrent reflux and re-intervention rates compared with both HLS and EVLA, whereas HLS and EVLA showed comparable performance across these outcomes. Long term quality of life was comparable across all groups.

Fourteen Year Outcomes of a Randomised Controlled Trial Comparing Endovenous Laser Ablation, High Ligation and Stripping, and Ultrasound Guided Foam Sclerotherapy for Great Saphenous Varicose Veins

Key Points

Abstract

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