Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring | Synapse
March 12, 2026Open Access
Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring
Key Points
The aim is to develop a hydrogel that releases growth factors to improve diabetic wound healing and minimize scars.
Developed interpenetrating network hydrogel using gelatin and sodium alginate.
Incorporated platelet-rich plasma (PRP) lysate for controlled delivery of growth factors.
Assessed the hydrogel's effectiveness in promoting tissue regeneration in diabetic wounds.
The hydrogel successfully controlled the release of PRP growth factors.
Diabetic wound healing was expedited with enhanced tissue regeneration.
Scarring was minimized compared to traditional treatments.
Abstract
Natural polymer based interpenetrating network hydrogel Gel/SA@PL released PL growth factors in a controlled manner to expedite diabetic wound healing with enhanced tissue regeneration and minimal scarring.