G‐ALPS: An index for evaluating cognitive decline and aging using diffusion tensor imaging

Key Points

• The aim is to evaluate cognitive decline and aging through the G-ALPS index, exploring its relation to brain function.
• Utilized diffusion tensor imaging to assess brain function.
• Developed the G-ALPS index for measuring cognitive decline.
• Analyzed the index in relation to the glymphatic system.
• The G-ALPS index may serve as an indirect measurement of glymphatic system function or dysfunction.