“Target species complex” concept: Strengthening environmental risk assessment of engineered gene drives | Synapse
April 1, 2026Open Access
“Target species complex” concept: Strengthening environmental risk assessment of engineered gene drives
Key Points
The aim is to improve environmental risk assessment methodologies for engineered gene drives targeting malaria vectors.
Developed a conceptual framework for assessing ecological risks.
Analyzed existing risk assessment methodologies.
Proposed criteria for evaluating target species interactions.
Identified key factors affecting ecological outcomes of engineered gene drives.
Demonstrated the need for a comprehensive assessment framework.
Highlighted gaps in current environmental risk assessments for genetic interventions.
Abstract
Competing interest statement: J.B.C. is a member of the Target Malaria not-for-profit research consortium, which is exploring the use of EGD for malaria vector