July 24, 2019Open Access

Routinely reported ejection fraction and mortality in clinical practice: where does the nadir of risk lie?

Structured PICO

Does deviation of LVEF from 60% to 65% affect survival in clinical practice?

Population

Patients in clinical practice with routinely reported left ventricular ejection fraction (LVEF)

Intervention

Deviation of LVEF from 60% to 65% (including supra-normal LVEF)

Comparator

LVEF of 60% to 65%

Outcome

Survival (mortality)hard clinical

Deviation of LVEF from the 60-65% range is associated with poorer survival, suggesting a potential new phenotype characterized by supra-normal LVEF.

Abstract

Deviation of LVEF from 60% to 65% is associated with poorer survival regardless of age, sex, or other relevant comorbidities such as heart failure. These results may herald the recognition of a new phenotype characterized by supra-normal LVEF.

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Cite This Study

Wehner et al. (Wed,) studied this question.

synapsesocial.com/papers/69d5709375589c71d767dd38 https://doi.org/https://doi.org/10.1093/eurheartj/ehz550

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