Why the study?
Does deviation of LVEF from 60% to 65% affect survival in clinical practice?
Does deviation of LVEF from 60% to 65% affect survival in clinical practice?
Deviation of LVEF from the 60-65% range is associated with poorer survival, suggesting a potential new phenotype characterized by supra-normal LVEF.
No immediate practice change; hypothesis-generating for supra-normal LVEF as distinct survival phenotype.
Deviation of LVEF from 60% to 65% is associated with poorer survival regardless of age, sex, or other relevant comorbidities such as heart failure. These results may herald the recognition of a new phenotype characterized by supra-normal LVEF.
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Wehner et al. (2019) studied this question.
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