Longitudinal study of genome-wide DNA methylation in individuals with and without post-acute symptoms following SARS-CoV-2 infection

Key Points

• This study aims to investigate epigenetic changes related to long-COVID and SARS-CoV-2 infection in different cohorts.
• Conducted a longitudinal analysis
• Examined genome-wide DNA methylation
• Compared individuals with and without post-acute symptoms
• No persistent epigenetic age differences were found
• No DNA methylation differences detected in cohorts due to long-COVID