Analysis of sonographic features in the differentiation of fibroadenoma and invasive ductal carcinoma.

A combination of tumor descriptors gave negative predictive values approaching 100%, allowing downgrading of solid breast masses with a high degree of confidence. Extensive sonographic features analysis in patients with indeterminate clinical and mammographic findings has the potential for downgrading a tumor and possibly obviating the need for excision in a subgroup of patients. Further investigations may provide standardization of sonographic descriptor analysis and establishment of the combination of the most predictive features that would be useful in daily practice.