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A combination of tumor descriptors gave negative predictive values approaching 100%, allowing downgrading of solid breast masses with a high degree of confidence. Extensive sonographic features analysis in patients with indeterminate clinical and mammographic findings has the potential for downgrading a tumor and possibly obviating the need for excision in a subgroup of patients. Further investigations may provide standardization of sonographic descriptor analysis and establishment of the combination of the most predictive features that would be useful in daily practice.
Skaane et al. (Thu,) studied this question.