Prognosis of Tricuspid Regurgitation after Mitral Transcatheter Edge-to-Edge Repair: The EXPANDed Studies
Key Result
Mitral transcatheter edge-to-edge repair led to early tricuspid regurgitation improvement to ≤moderate in almost 75% of patients, providing significant symptomatic relief.
Key Points
This analysis aims to assess the prognosis of tricuspid regurgitation (TR) after mitral transcatheter edge-to-edge repair (MTEER).
Observed population with tricuspid regurgitation following MTEER
Evaluation of TR improvement and symptomatic outcomes
Identification of factors influencing TR, including mitral regurgitation and left ventricular dilation
Approximately 75% of patients showed early improvement in TR to moderate levels
Significant symptomatic relief was noted post-procedure
Patients with severe mitral and tricuspid regurgitation, especially with left ventricular dilation, benefitted most from the intervention
Structured PICO
Does mitral transcatheter edge-to-edge repair improve tricuspid regurgitation and symptoms in patients with concomitant mitral and tricuspid regurgitation?
P
Population
Patients with tricuspid regurgitation (TR) undergoing mitral transcatheter edge-to-edge repair (MTEER), including those with severe mitral regurgitation (MR), severe TR, and left ventricular (LV) dilation.
I
Intervention
Mitral Transcatheter Edge-to-Edge Repair (MTEER)
O
Outcome
Early TR improvement to ≤moderate and symptomatic reliefsurrogate
Mitral transcatheter edge-to-edge repair is associated with early improvement in concomitant tricuspid regurgitation and symptomatic relief, particularly in patients with severe MR, TR, and LV dilation.
Main Result
Absolute Event Rate: 0% vs 0%
Abstract
Early TR improvement to ≤moderate was observed in almost 3/4 of the population and was associated with significant symptomatic relief. Patients with both severe MR and TR, particularly those with LV dilation, may experience TR improvement following MTEER.
Estevez-Loureiro et al. (Tue,) reported a other. Mitral transcatheter edge-to-edge repair led to early tricuspid regurgitation improvement to ≤moderate in almost 75% of patients, providing significant symptomatic relief.