Efficacy of a Hyaluronic Acid‐Based Gel Versus 0.20% Chlorhexidine in Nonsurgical Periodontal Therapy: A Single‐Blind Randomized Clinical Trial

Key Points

• The aim is to determine the efficacy of a hyaluronic acid-based gel compared to 0.20% chlorhexidine in nonsurgical periodontal therapy.
• Single-blind randomized clinical trial design
• Comparison between hyaluronic acid gel and chlorhexidine
• Assessment of periodontal parameters like PPD and CAL
• Hyaluronic acid gel significantly improved probing pocket depth (PPD)
• Enhanced clinical attachment level (CAL) observed with HA gel
• Demonstrated safety and clinical benefits over chlorhexidine