The present study aimed to assess the effect of preoperative prealbumin-bilirubin (preALBI) levels on this risk. 585 patients with HCC undergoing major hepatectomy were included. Multivariable analysis was conducted to identify the prognostic factors. The predictive performance for morbidity was assessed. The baseline characteristic showed that patients in the high preALBI group exhibited significantly poorer liver function and showed a higher risk of intraoperative bleeding and blood transfusion. Multivariate analysis revealed that preALBI grade is an independent risk factor for overall (OR 1.517, P = 0.001) and major (OR 1.491, P = 0.015) morbidity. Moreover, the preALBI score demonstrates better predictive ability for overall and major morbidity compared to other indicators (all P < 0.05). PALBI is a reliable predictor of postoperative morbidity in patients with HCC undergoing major hepatectomy. Incorporating PALBI into preoperative assessments could enhance risk stratification and improve patient management.
Shi et al. (Wed,) studied this question.
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