NMS-associated rhabdomyolysis-induced AKI complicated by sepsis and contrast exposure led to prolonged renal replacement therapy, with dialysis independence achieved only after 2 months.
Case Report (n=1)
NMS-associated rhabdomyolysis-induced AKI can require prolonged hemodialysis, especially when compounded by other renal insults like sepsis and contrast exposure.
Neuroleptic malignant syndrome (NMS) can be complicated by rhabdomyolysis, a known cause of acute kidney injury (AKI) that typically resolves within a short period. However, some cases of NMS-associated rhabdomyolysis require hemodialysis. We report a woman in her fifties who developed AKI secondary to NMS-associated rhabdomyolysis and required prolonged renal replacement therapy (RRT). She experienced sepsis and contrast exposure, and dialysis independence was achieved only after 2 months, the longest reported duration. This case highlights that NMS-associated rhabdomyolysis-induced AKI may lead to prolonged dialysis, particularly in the presence of additional risk factors for renal injury.
Nakata et al. (Thu,) conducted a case report in Neuroleptic malignant syndrome-associated rhabdomyolysis with acute kidney injury (n=1). Renal replacement therapy (hemodialysis) was evaluated on Dialysis independence. NMS-associated rhabdomyolysis-induced AKI complicated by sepsis and contrast exposure led to prolonged renal replacement therapy, with dialysis independence achieved only after 2 months.
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