A fully automated multiplex PCR panel for detecting CNS pathogens in cerebrospinal fluid demonstrated 92.9% positive and 91.9% negative agreement compared to routine testing.
Does a multiplexed PCR panel accurately detect CNS pathogens in cerebrospinal fluid compared to routine testing?
A multiplexed PCR panel demonstrated high positive (92.9%) and negative (91.9%) agreement with routine testing for detecting CNS pathogens in cerebrospinal fluid.
Absolute Event Rate: 0% vs 0%
We evaluated a multiplexed PCR panel for the detection of 16 bacterial, viral, and fungal pathogens in cerebrospinal fluid. Panel results were compared to routine testing, and discrepancies were resolved by additional nucleic acid amplification tests or sequencing. Overall, the positive and negative agreements across methods were 92.9% and 91.9%, respectively.
Hanson et al. (Thu,) reported a other. A fully automated multiplex PCR panel for detecting CNS pathogens in cerebrospinal fluid demonstrated 92.9% positive and 91.9% negative agreement compared to routine testing.