Key result
A fully automated multiplex PCR panel for detecting CNS pathogens in cerebrospinal fluid demonstrated 92.9% positive and 91.9% negative agreement compared to routine testing.
Why the study?
Does a multiplexed PCR panel accurately detect CNS pathogens in cerebrospinal fluid compared to routine testing?
Population
Cerebrospinal fluid samples
Comparison
Multiplexed PCR panel for the detection of 16… vs Routine testing
Design
Preclinical
Authors
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Animal data support human validation trials; leaves open clinical adoption for CNS pathogen detection.
Does a multiplexed PCR panel accurately detect CNS pathogens in cerebrospinal fluid compared to routine testing?
A multiplexed PCR panel demonstrated high positive (92.9%) and negative (91.9%) agreement with routine testing for detecting CNS pathogens in cerebrospinal fluid.
Hanson et al. (2015) studied this question. A fully automated multiplex PCR panel for detecting CNS pathogens in cerebrospinal fluid demonstrated 92.9% positive and 91.9% negative agreement compared to routine testing.
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