Abstract Introduction Peyronie's disease (PD) and congenital penile curvature (CPC) significantly impacts erectile function, sexual quality of life, and psychological well-being of men. Surgical intervention continues to represent the definitive therapeutic approach in stable cases presenting with clinically meaningful anatomical deformity. Objective This study aims to evaluate the real-world effectiveness, safety, and patient-reported outcomes of various corporoplasty techniques at a tertiary referral center. Methods Data from 324 sexually active men surgically treated for penile curvature between 2020 and 2025 at Fundació Puigvert in Barcelona were retrospectively analyzed. Preoperative data, surgical techniques, and clinical characteristics were collected. Patient-reported outcomes were assessed by telephone 6 to 48 months postoperatively using the Global Assessment Questionnaire (GAQ), and supplementary satisfaction questions (SQ). Descriptive statistics was applied. Results Of 324, 274 (84.6%) patients presented with PD and 50 (15.4%) with CPC, respectively. The median age of the entire population was 51 (IQR 18–72) years. Surgical techniques were 16-dot plication performed in 159 patients (49%), Yachia in 81 (25%), modified Nesbit in 65 (20%) and lengthening procedures with Surgisis patch in 19 (6%), respectively. According to the GAQ, 211 patients (65%) reported an improvement in sexual quality of life following surgery, whereas 55 (17%) experienced no change and 58 (18%) reported a deterioration. Based on GAQ-2 responses, 159 individuals (49%) noted enhanced ability to achieve/maintain erections, 100 (31%) reported no change, and 62 (19%) experienced worsening. Regarding the SQ, 249 (77%) patients expressed satisfaction with the surgical outcomes, 259 (80%) considered the penile curvature to be adequately corrected, and 256 (79%) indicated they would recommend the procedure to others. Overall, complications occurred in 67 (20.7%) patients. Complication rates were highest following the Yachia procedure, with 23 patients (28.4%) affected; the most frequent adverse events included edema in 7 cases (30.4%) and hematoma in 6 (26%). Among those who underwent 16-dot plication, 28 patients (17.6%) experienced complications, most commonly edema (7 cases, 25%), infection (7 cases, 25%), and hematoma (6 cases, 21.4%). After modified Nesbit surgery, 12 patients (18.5%) reported adverse outcomes, including edema in 6 cases (50%) and decreased penile sensitivity in 4 (33.3%). Regarding grafting procedures, complications were observed in 4 patients (21%) treated with Surgisis patch, with decreased sensitivity and hematoma each occurring in 2 cases (10.5%). Conclusions Corporoplasty for PD and CPC demonstrated robust real-world effectiveness with acceptable postoperative morbidity. Disclosure No
Raffo et al. (Mon,) studied this question.
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