The research focuses on understanding the risk and management of contrast-induced acute kidney injury (CI-AKI) in patients undergoing cardiac imaging.
Review of epidemiology and pathophysiology of CI-AKI
Analysis of outcome implications including renal replacement therapy and rehospitalization
Discussion on management strategies in the cardiac catheterization laboratory
CI-AKI is associated with increased risk of renal replacement therapy and rehospitalization.
Severity of CI-AKI correlates with higher mortality rates in affected patients.
The review highlights the need for preventive strategies in at-risk populations.
Abstract
Coronary angiography and percutaneous intervention rely on the use of iodinated intravascular contrast for vessel and chamber imaging. Despite advancements in imaging and interventional techniques, iodinated contrast continues to pose a risk of contrast-induced acute kidney injury (CI-AKI) for a subgroup of patients at risk for this complication. There has been a consistent and graded signal of risk for associated outcomes including need for renal replacement therapy, rehospitalization, and death, according to the incidence and severity of CI-AKI. This paper reviews the epidemiology, pathophysiology, prognosis, and management of CI-AKI as it applies to the cardiac catheterization laboratory.