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Cerebral venous oxygenation (Yv) is a biomarker in various brain diseases such as hypoxic-ischemic-encephalopathy in neonates and Alzheimer's disease in the elderly. T2-Relaxation-Under-Spin-Tagging (TRUST) MRI is a widely used technique to measure global Yv level. However, subject motion during TRUST scan can cause considerable errors in Yv quantification. This work developed an automatic algorithm for motion-corrected quantification of Yv, which showed improved precision of Yv estimation in both neonates and elderly adults.
Gou et al. (Wed,) studied this question.
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