IFOM

Recent papers from IFOM

1. Extracellular matrix stiffness controls Transposable Elements through Pin1 to promote immune evasion in breast cancerCancer Discovery · 2026
2. Targeting ERO1α triggers tumor immunosurveillance in triple-negative breast cancerRedox Biology · 2026
3. Coordinated regulation of nuclear integrity and STING trafficking by miR-30d suppresses innate immunity in breast cancerNature Communications · 2026
4. Human iPSC-derived liver organoid model multicellular tissue responses and therapeutic rescue in Wolman diseaseCell Death and Disease · 2026
5. BMI1 Inhibition Improves Lesion Burden in Cerebral Cavernous MalformationsCirculation · 2024
6. Single‐Cell Analysis of Cartilage‐Derived Cells Identifies Diverse Populations and a Cholesterol/ER‐Stress Chondrocyte Subset in Knee OAJournal of Orthopaedic Research® · 2026
7. RNAmotifs 2.0: a framework for inferring multivalent RNA motifs and their candidate regulators of splicingBMC Biology · 2026
8. Patient-derived separation-of-function mutations reveal specific role for BRCA1 coiled coil domain in genome stabilityNature Communications · 2026
9. Clinical evaluation of AI-assisted quantitative marrow fibrosis assessment using Continuous Indexing of Fibrosis (CIF)Leukemia · 2026
10. Circulating tumor DNA-guided de-escalation or escalation of adjuvant therapy in high-risk stage II and stage III colon cancer: the phase 2 PEGASUS trialNature Cancer · 2026
11. Contact percolation governs collective motility via mechano-chemical feedback in heterogeneous breast cancerNature Communications · 2026
12. PHAROS: turning single-cell perturbation models into target-directed drug-combination screens2026
13. Microbiome alterations in mismatch-repair deficient metastatic colorectal cancer patientsScientific Reports · 2026
14. Transcriptomic profile and endothelial changes during differentiation syndrome in acute promyelocytic leukemiaAnnals of Hematology · 2026
15. Multimodal spatial profiling reveals distinct myeloid-defined ENKTL subgroups and tumor-myeloid cooperativity within prognostic inflammatory nicheLeukemia · 2026
16. Chromatin condensates tune nuclear mechanosensing and preserve nuclear integrity to prevent cGAS activationThe EMBO Journal · 2026
17. The telomeric DNA damage response as a therapeutic target in idiopathic pulmonary fibrosisEMBO Molecular Medicine · 2026
18. The Dynamic Alliance of p53 and Metabolism in the Tumor Microenvironment Shapes Tumor EvolutionBioEssays · 2026
19. Heteroplasmic variants of mitochondrial genome in tumor and normal samples from patients with hematologic malignanciesLeukemia · 2026
20. Targeting DNA interstrand crosslinks repair with synthetic lethality in High-Grade B-Cell LymphomaLeukemia · 2026