Gwynedd Council

Recent papers from Gwynedd Council

1. Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined DevelopmentClinical Pharmacology & Therapeutics · 2026
2. 2347-P: Sleep Duration, Sleep Quality, and Associated Factors in a Nationally Representative Sample of U.S. Adults with DiabetesDiabetes · 2026
3. Overcoming claudin family homology: discovery of ARC101, a highly potent CLDN6-specific T-cell engager with a novel CD3 binder for ovarian adenocarcinoma.2026
4. Organoids in drug development: from predictive models to regulatory integrationDrug Discovery Today · 2026
5. Conserving key coastal areas for mangrove expansion and eco-tourism secures ecosystem services under sea-level risenpj Ocean Sustainability · 2025
6. 2025 White Paper on Recent Issues in Bioanalysis: Redosing Patients with AAV Gene Therapy; CRS Immunogenicity Risk; Shedding Assays; NHP Studies Immunogenicity; CMC vs Bioanalytical Assays; Artificial Intelligence-Powered Genomic Pipelines for NGS ( PART 3A – Recommendations on Gene, Cell, and Vaccine Therapies Immunogenicity & Technologies; Biotherapeutics & Biosimilars Immunogenicity Assessment & Clinical Relevance PART 3B – Regulatory Agencies’ Input on Immunogenicity/Technologies of Biotherapeutics, Gene, Cell & Vaccine Therapies)Bioanalysis · 2025
7. Infection of ratites with clade 2.3.4.4b HPAIV H5N1: Potential implications for zoonotic risk2025
8. Efficacy and preliminary safety assessment of EXG001-307 AAV gene therapy for spinal muscular atrophyMolecular Therapy — Methods & Clinical Development · 2025
9. IFI16 senses and protects stalled replication forks2025
10. Assessment of the Anchovy Stock Using a Beverton–Holt‐Driven Production Model in China Waters of the Bohai and Yellow SeasFisheries Management and Ecology · 2025
11. What do data rights do for workers? A critical analysis of trade union engagement with the datafied workplaceTransfer European Review of Labour and Research · 2024
12. Youth Justice Staff Perspectives on Psychological Resilience Interventions and Outcomes in Young People Who OffendDeviant Behavior · 2024
13. Short Sleep Duration Disrupts Glucose Metabolism: Can Exercise Turn Back the Clock?Exercise and Sport Sciences Reviews · 2024
14. How age and sex affect treatment outcomes for children with severe malnutrition: A multi‐country secondary data analysisMaternal and Child Nutrition · 2023
15. Impact of Various Estimated Glomerular Filtration Rate Equations on the Pharmacokinetics of Meropenem in Critically Ill AdultsCritical Care Explorations · 2023
16. Lasso penalisation identifies consistent trends over time in landscape and climate factors influencing the wintering distribution of the Eurasian Curlew (Numenius arquata)Ecological Informatics · 2023
17. Efficacy of Baduanjin for treatment of fatigue: A systematic review and meta-analysis of randomized controlled trialsMedicine · 2023
18. A new species of Lethrinops (Cichliformes: Cichlidae) from a Lake Malawi satellite lake, believed to be extinct in the wild.Zootaxa · 2023
19. PET-validated EEG-machine learning algorithm predicts brain amyloid pathology in pre-dementia Alzheimer’s diseaseScientific Reports · 2023
20. Immune restoration with ibrutinib plus venetoclax in first-line chronic lymphocytic leukemia: the phase 2 CAPTIVATE studyBlood Advances · 2023