Huntington's Disease Association

Recent papers from Huntington's Disease Association

1. HD ‐ DRUM Rhythmic Training in Huntington's Disease: Feasibility, Motor, and Brain Microstructural Pilot SignalsMovement Disorders Clinical Practice · 2026
2. Cas9 nickase–mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington’s disease mouse modelScience Translational Medicine · 2026
3. Tick species infesting rock partridges (Alectoris graeca Meisner, 1804) in CroatiaCroatian veterinary journal · 2026
4. Psychological interventions for individuals affected by Huntington’s disease: effects on depression, anxiety, and emotional well-beingJournal of Community Genetics · 2026
5. Why is family disclosure of genetic risk so difficult? A collaborative analysis of 685 rare-disease patient experiencesEuropean Journal of Human Genetics · 2026
6. Blocking somatic repeat expansion and lowering huntingtin by RNAi synergize to attenuate Huntington’s disease pathogenesis in miceScience Translational Medicine · 2026
7. Early Longitudinal Brain Network Changes in Huntington's Disease Before Clinical Motor OnsetMovement Disorders · 2026
8. Nuclear RNA clusters are dynamic structural entities in Huntington’s diseaseCommunications Biology · 2026
9. Molecular features of a Huntington's disease knock-in minipigDisease Models & Mechanisms · 2026
10. The holistic burden of Huntington's disease: A qualitative study of multigenerational impact on individuals and family caregivers across EuropeJournal of Huntington s Disease · 2026
11. Retrospective multicenter analysis of causes of death in wild mammals in Southern Germany (2019–2023)Frontiers in Veterinary Science · 2026
12. IDEA-FAST clinical study protocol: Identifying digital end-points of fatigue, sleep quality and daytime sleepiness in N = 2000Digital Health · 2026
13. Selective targeting of mutant huntingtin intron 1 improves rescue provided by antisense oligonucleotides in Huntington’s disease miceScience Translational Medicine · 2026
14. Lowering the HTT1a transcript as an effective therapy for Huntington’s disease in a knockin mouse modelScience Translational Medicine · 2026
15. Experiences and perceptions of affected individuals, families, caregivers and healthcare professionals regarding end-of-life planning in Huntington's disease: A narrative synthesisJournal of Huntington s Disease · 2026
16. The HTT1a protein initiates HTT aggregation in a knock-in mouse model of Huntington’s diseaseBrain · 2026
17. Discovery of disrupted sustained attention and altered functional connectivity in far‐from‐onset Huntington's disease gene‐expanded young adultsAlzheimer s & Dementia · 2026
18. Enhancing the detection of HTT1a with neoepitope antibodies in mouse models of Huntington’s diseaseBrain Communications · 2026
19. Mapping Regional Brain Aging in Huntington's Disease Using Structural Magnetic Resonance Imaging and Machine LearningMovement Disorders · 2025
20. Neural and biomarker correlates of the Parkinson's Disease–Cognitive Rating Scale in Huntington's diseaseNeuroimage Reports · 2025