Sleep Management Institute

Recent papers from Sleep Management Institute

1. Oveporexton for Narcolepsy Type 1 — Results from Two Phase 3 TrialsNew England Journal of Medicine · 2026
2. Cardiovascular and Cardiometabolic Comorbidities in Central Disorders of Hypersomnolence: A Narrative ReviewSleep Medicine Reviews · 2026
3. Long-term Safety and Efficacy of Extended-release Once-nightly Sodium Oxybate for Narcolepsy in Patients not Currently Taking an Oxybate (P6-14.004)Neurology · 2026
4. Once-nightly Sodium Oxybate Improves Symptoms in People With Narcolepsy: Interim Results From the Real-world REFRESH Study (P6-14.007)Neurology · 2026
5. E2086, a Selective Orexin Receptor Two Agonist: Study for Promoting Wakefulness in Patients With Narcolepsy Type One (P6-14.003)Neurology · 2026
6. Real-world effectiveness and safety of tonic motor activation therapy for refractory restless legs syndrome: 90-day outcomes from the THRIVE prospective observational studySLEEP · 2026
7. 0794 Long-Term Real-World Outcomes of Tonic Motor Activation (TOMAC) for Refractory Restless Legs Syndrome (RLS): Interim 1-Year Data from the THRIVE StudySLEEP · 2026
8. 0766 Real-World Experience of Once-Nightly Sodium Oxybate Treatment in People with Narcolepsy: Final Results from REFRESHSLEEP · 2026
9. 0440 Real World Evidence of Non-Invasive Vestibular Nerve Stimulation for InsomniaSLEEP · 2026
10. 0752 Once-Nightly Sodium Oxybate Improves Symptoms in People with Narcolepsy: Final Results from the Real-World REFRESH StudySLEEP · 2026
11. 0765 Oxybate Treatment Experience and Preferences of People with Idiopathic HypersomniaSLEEP · 2026
12. 0792 Efficacy and Temporal Trajectory of Tonic Motor Activation in Painful and Painless Restless Legs: Interim 270-Day Results from the THRIVE StudySLEEP · 2026
13. 0740 Solriamfetol for Excessive Daytime Sleepiness in Narcolepsy and OSA: Post-hoc Multi-dimensional Composite Endpoint Analysis of Phase 3 TrialsSLEEP · 2026
14. 1143 Cognitive Outcomes of 12-Month CPAP Therapy in Amnestic Mild Cognitive Impairment (MCI)SLEEP · 2026
15. Skin thermal dynamics and hypothalamic thermosensitivity dissociate REM sleep and cataplexy in narcolepsyScience Translational Medicine · 2026
16. Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorderBritish Journal of Clinical Pharmacology · 2025
17. Molecular requirements for C. elegans transgenerational epigenetic inheritance of pathogen avoidanceeLife · 2025
18. 0866 Effect of Pitolisant on Idiopathic Hypersomnia Symptoms During a Double-Blind Withdrawal Period in a Phase 3 TrialSLEEP · 2025
19. Molecular requirements for C. elegans transgenerational epigenetic inheritance of pathogen avoidanceeLife · 2025
20. Fatigue is distinct from sleepiness and negatively impacts individuals living with obstructive sleep apnea (OSA): results from qualitative research of individuals with OSAHealth and Quality of Life Outcomes · 2025