Charles River Laboratories (Germany)

Recent papers from Charles River Laboratories (Germany)

1. Regulatory Case Studies Encountered by Project Toxicologists in Drug DevelopmentInternational Journal of Toxicology · 2026
2. Pharky, Phedro, Phractured, and StagePhright: complete genome sequences of four EK2 cluster Microbacterium phagesMicrobiology Resource Announcements · 2026
3. The ITCC-P4 PDX Platform Enables Preclinical Testing of Pediatric CancersCancer Research · 2026
4. MicroOrganoSphere™ technology to advance drug screening in neuroblastoma precision medicineEJC Paediatric Oncology · 2026
5. 18 th GCC Closed Forum: Compliance with FDA Biomarkers Guidance, Novel ELN/LIMS Platforms, Sample Reconciliation, Emerging Technologies, Improvements in ELISpot, Post-extraction Sample Stability, LBA Singlicate, Regulatory Inspections, Chicken anti-Human IgG, Cross-validation HarmonizationBioanalysis · 2026
6. Overcoming Access Barriers in European CAR-T Therapy: The Role of Decentralized Manufacturing and the EASYGEN FrameworkENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) · 2026
7. PrP turnover in vivo and the time to effect of prion disease therapeuticsPLoS Pathogens · 2026
8. Inhaled Virus-Mimicking Particles Elicit Dose-Dependent Immune Response against SARS-CoV-2 with Sex-Bias ACE2 Activity in MiceNano Letters · 2026
9. Safety Evaluation of Intranasal Nalmefene in Juvenile Rat Studies in Support of Clinical Trials in Pediatric Patients From Birth to 12 Years of AgeInternational Journal of Toxicology · 2026
10. 10 × Genomics Flex Gene Expression is a powerful tool for single-cell transcriptomics of xenografts modelsGenome biology · 2026
11. An update on the European Bioanalysis Forum recommendation on singlicate analysis for ligand binding assays: biomarker and anti-drug-antibody assaysBioanalysis · 2026
12. Abstract 3420: DoE-based optimization of transposon-based gene insertion using the Harbor-IN systemCancer Research · 2026
13. Abstract 2113: Optical imaging and digital pathology evaluation increases the translational value and robustness of patient-derived metastatic breast cancer models.Cancer Research · 2026
14. Abstract 3400: A 3D bioprinted hydrogel-based tumor model of non-small cell lung cancer for preclinical drug testingCancer Research · 2026
15. Abstract 3372: Predictive in vitro assays and PBMC donor banking: reducing variability in humanized mouse studiesCancer Research · 2026
16. Abstract 731: From hours to seconds: a new tool for accelerating in vivo rodent imaging data analysis using AI algorithms.Cancer Research · 2026
17. Abstract 2175: Towards ethical and robust drug development: comprehensive validation of an animal-free matrix for in vivo tumor models.Cancer Research · 2026
18. Abstract 4874: Preclinical assessment of HER2 CAR-T cells using tumor and GI organoid models to define therapeutic windowCancer Research · 2026
19. Abstract 299: From factory to patient: In vivo -expressed biologics as a new paradigm for immunotherapy manufacturing.Cancer Research · 2026
20. HGG-07. Combination of CDK4/6 and MEK inhibition increases antitumor effects in pediatric high-grade glioma harboring concomitant BRAF mutation and CDKN2A/B lossNeuro-Oncology Pediatrics · 2025