National Institutes of Pharmaceutical Research and Development (China)

Recent papers from National Institutes of Pharmaceutical Research and Development (China)

1. Bispecific antibodies targeting TL1A and IL-12/23p40 suppress pathogenic Th1/Th17 responses and ameliorate colitis in miceiScience · 2026
2. Phocaeicola dorei YGMCC0564 attenuates HFD-induced glycolipid metabolic disorders in association with remodeling of the gut microbiota and bile acid profilesFrontiers in Microbiology · 2026
3. Pharmacokinetic and safety interactions between aildenafil and clarithromycin, cimetidine, or rifampin in healthy subjectsBritish Journal of Clinical Pharmacology · 2026
4. Research Advances on Organelle-Targeted Drug Delivery Systems for the Treatment of Brain Tumors and Central Nervous System InflammationPharmaceutics · 2026
5. Network pharmacology, and molecular docking studies for two flavonoid compounds isolated from Dodonaea viscosa towards SARS-CoV-2 infection and loaded in lipid nanoparticlesArtificial Cells Nanomedicine and Biotechnology · 2026
6. Detection of Residual Pluripotent Stem Cells in Differentiated Cells—General Requirements for Probe‐Based Quantitative PCR AssayCell Proliferation · 2026
7. Testing for Bacteria and Fungi in Cells and Ancillary Reagents—Probe‐Based Quantitative PCR AssaysCell Proliferation · 2026
8. Pharmacokinetics, pharmacodynamics and safety profile of tapentadol hydrochloride injection: a phase 1 dose-escalation study in patients with moderate to severe painScientific Reports · 2026
9. From Static Scaffolds to Responsive Implants: 3D‐Printed Field‐Active Bioceramics for Adaptive Bone RegenerationAdvanced Healthcare Materials · 2026
10. Self‐Cooperative RNA Vaccine Mitigates Dendritic Cell–Mediated Acquired Immune Resistance to Potentiate Cell Therapy for Solid TumorsAdvanced Materials · 2026
11. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors: Mechanisms, Therapeutic Applications, and Developmental ProgressKidney Medicine · 2026
12. AI in pharmacy education: a comparative visualization analysis of global and Chinese research trendsFrontiers in Medicine · 2026
13. Lyophilizable Thermostable Nano‐Aluminum Adjuvant and Combinations Induced Robust Antigen‐Specific Humoral and Cellular Immunity in MiceAdvanced Healthcare Materials · 2026
14. Natural history and 12-month progression of multiple system atrophy in a Chinese cohortBMC Neurology · 2026
15. Discovery of an orally active and liver-targeted dual prodrug of 5-fluoro-2′-deoxyuridine-5′-monophosphate for the treatment of hepatocellular carcinomaAnti-Cancer Drugs · 2026
16. Harpagide attenuates cerebral ischemic injury by modulating mitochondrial calcium homeostasis associated with the AMPK–MCU axisScientific Reports · 2026
17. Inference of upstream-mutation and metabolomic-signature causality identifies prognostic biomarkers and therapeutic targets in pancreatic cancerNature Communications · 2026
18. Phase I/IIa study of DN022150, a novel selective noncovalent small molecule KRAS G12D inhibitor in patients with advanced KRAS G12D–mutant solid tumors.Journal of Clinical Oncology · 2026
19. Integrated MALDI-MSI and UHPLC-OE-MS for Spatial Visualization and Biosynthetic Pathway Elucidation of Bioactive Metabolites in Lilium lancifolium Thunb.Molecules · 2026
20. Unraveling the Gut Microbiota-Mediated Mechanism of Guogong Jiu for Rheumatoid Arthritis Treatment through Network Pharmacology and MetabolomicsCurrent Drug Metabolism · 2026